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Symex CML500

The Symex CML 500 is a high-performance vacuum homogeniser mixer designed for the production of demanding products in the pharmaceutical and cosmetics industries.

This unit combines mixing, dispersing, homogenising, heating, cooling, and vacuum processing in a closed system, enabling precise and reproducible production—from pilot-scale to industrial applications. Such systems are specifically engineered for complex processes with high quality requirements.

Technical Highlights of the Symex CML 500

Tank
- Usable volume: approx. 500 litres
- Total volume: approx. 780 litres
- Minimum volume: approx. 125–160 litres
- Product chamber pressure range: -1 / +2 bar
- Product temperature: up to approx. 133°C
- Heating jacket: up to +4 bar / 151°C
- Designed in accordance with AD 2000
- The tank is fully rated for both pressure and vacuum to ensure safe operation under demanding conditions.

Agitator
- Anchor agitator with flow breakers
- Speed range: approx. 11–66 rpm
- Power: approx. 7.5 kW
- Frequency-controlled
- Suitable for highly viscous products
- The agitator ensures uniform mixing and optimal heat transfer.

Homogeniser
- Power: approx. 16–20 kW
- Speed: up to approx. 3,000 rpm
- High shear force for fine dispersion
- Rotor/stator system
- The homogeniser ensures stable emulsions and consistent product quality.

Vacuum System
- Vacuum operation possible
- Liquid ring vacuum pump (external)
- Pressure and vacuum monitoring
- Vacuum operation significantly reduces air ingress and greatly improves product quality.

Heating & Cooling
- Double-walled tank (2-zone heating)
- Precise temperature control
- Even heat distribution
- CIP system

Multiple CIP Connections
- Rotating spray cleaning nozzles (360°)
- Cleaning of the entire product chamber including pipework

Raw Material Feed
- Direct suction of liquids and powders
- Suction directly into the homogeniser area
- Fast and low-loss processing
- Integrated dosing and recirculation systems enable highly efficient processing.

Additional Equipment
- Hydraulic lid lifting device
- Multi-nozzle bell with several connection options
- Sight glass with dual wiper
- Interior tank lighting
- Dosing vessel (approx. 8 litres)
- Sampling valve
- Diaphragm and disk valves
- Recirculation piping for homogenisation and CIP

Control & Operation

The unit features a modern operating concept:
- Touch panel control
- Adjustable speeds and run times
- Process monitoring (pressure, temperature, speed)
- Automatic and manual operating modes
- Alarm messages and safety functions

Advantages of the Symex CML 500

- All process stages combined in a single system
- High process reliability due to closed design
- Reproducible and stable product quality
- Suitable for highly viscous and sensitive products
- Hygienic design (GMP compliant)
- Flexible use for various batch sizes

Delivery & Handling
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- Delivery ex-works
- Turn-key project available (including commissioning)
- International shipping possible

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